Adeno - Associated Virus - RNAi of GlyR α 1 and Characterization of Its Synapse - specific
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چکیده
Running Title: Glycine receptor subunit specific inhibition & retinal signaling 3 Zhang, C. , Rompani, S.B., Roska, B. and McCall, M.A. 2 4 5 Departments of Ophthalmology and Visual Science, Anatomical Sciences and Neurobiology, 6 University of Louisville, Louisville, KY 40202. 7 Neural Circuit Laboratories, Friedrich Miescher Institute for Biomedical Research, 4058 Basel, 8 Switzerland 9
منابع مشابه
Adeno-associated virus-RNAi of GlyRα1 and characterization of its synapse-specific inhibition in OFF alpha transient retinal ganglion cells.
In the central nervous system, inhibition shapes neuronal excitation. In spinal cord glycinergic inhibition predominates, whereas GABAergic inhibition predominates in the brain. The retina uses GABA and glycine in approximately equal proportions. Glycinergic crossover inhibition, initiated in the On retinal pathway, controls glutamate release from presynaptic OFF cone bipolar cells (CBCs) and d...
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تاریخ انتشار 2014